Gastric Ulcers Related to The Transarterial Radioembolization of Yittrium-90 in A Patient with Paraganglioma

Paragangliomas (PGLs) are neuroendocrine tumors that arise from extra-adrenal neuroendocrine cells. Liver metastases of PGL which are not candidates for surgical resection can be treated by transarterial chemoembolization (TACE) when it is technically feasible (1). Selective internal radiation therapy (SIRT), in other words, radioembolization (RE) with biocompatible resin-based yttrium 90 (Y90)-labeled microspheres, administered via hepatic artery branches, is a method used to selectively deliver internal radiation therapy to liver metastases (2). However RE, has the potential to cause extrahepatic adverse effects if the microspheres are incorrectly delivered to arteries supplying the stomach, duodenum, or pancreas, as well as other organs. We present here a case of metastatic PGL with gastroduodenal ulcerations related to Y90 RE.